Introduction: history, time line; Microbial growth kinetics: Batch, continuous and Fed-batch cultures; Microorganism: Isolation, preservation and strain improvement; Media for industrial fermentations: nutrient sources, design & optimization by Design of experiments; Sterilization: Design of batch and continuous sterilization of medium, bioreactor, filter sterilization of process streams; Inoculum development;Sold state fermentation; Bioprocess monitoring and measurement.
Fundamentals of enzymology: classification, chemical mechanisms of enzyme catalysis; kinetics of single-substrate and multi-substrate enzyme catalysed reactions; enzymatic production of valuable molecules in batch operation;Process technology for the production of: Baker’s yeast, ethanol, organic acids, antibiotics and high fructose corn syrup.